Epigenetics corresponds to the modification of gene expression which do not arise from modifications of the DNA sequence. The most important events are : DNA methylation at CpG islets and post-translational modification of histones (methylation, acetylation, phosphorylation,...). Epigenetic events are strongly influenced by environmental factors, stress and diets.
Exploring these events can help you to understand gene regulation, activation of signaling pathways and explain many physiological (like development and growth) or pathological processes.
AnyGenes® offers you several ranges of services which allow analysis of epigenetic events.
- By quantifying gene expression for enzymes involved in epigenetic events by qPCR arrays (SignArrays®).
- By assessing methylation of CpG islets with pyrosequencing technology.